Does detection of anti-AQP4 antibodies trump clinical criteria for neuromyelitis optica?
نویسندگان
چکیده
منابع مشابه
White matter in traumatic brain injury: Dis- or dysconnection?
810 White matter in traumatic brain injury: Disor dysconnection? Pieter E. Vos and Erin D. Bigler 812 Does detection of anti-AQP4 antibodies trump clinical criteria for neuromyelitis optica? Brian G. Weinshenker and William M. Carroll 814 Do neurologists make a difference in Parkinson disease care? James F. Burke and Roger L. Albin 816 Further restrictions on resident duty hours: Let’s look bef...
متن کاملSjögren syndrome and neuromyelitis optica spectrum disorder co-exist in a common autoimmune milieu.
The relationship between Sjögren's syndrome (SS) and neuromyelitis optica spectrum disorder (NMOSD) is not completely understood. We report two patients with both conditions and review 47 other previously reported cases meeting currently accepted diagnostic criteria, from 17 articles extracted from PubMed. Out of 44 patients whose gender was informed, 42 were females. Mean age at onset of neuro...
متن کاملAquaporin-4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitis.
BACKGROUND There is increasing recognition of antibody-mediated immunotherapy-responsive neurologic diseases and a need for appropriate immunoassays. OBJECTIVES To develop a clinically applicable quantitative assay to detect the presence of aquaporin-4 (AQP4) antibodies in patients with neuromyelitis optica and to characterize the anti-AQP4 antibodies. DESIGN We compared a simple new quanti...
متن کاملAssociation Between Helicobacter Pylori Infection and Seronegative Neuromyelitis Optica Spectrum Disorder
Background: Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune demyelinating disease in the central nervous system. Association between NMOSD and Helicobacter pylori (H. pylori) infection has been investigated, but few studies have assessed the relationship between H. pylori and seronegative AQP4-Ab NMOSD. Objectives: This study aimed to survey the association between H. pylori...
متن کاملAn immunoassay that distinguishes real neuromyelitis optica signals from a labeling detected in patients receiving natalizumab
BACKGROUND Cell-based assays for neuromyelitis optica (NMO) diagnosis are the most sensitive and specific methods to detect anti-aquaporin 4 (AQP4) antibodies in serum, but some improvements in their quantitative and specificity capacities would be desirable. Thus the aim of the present work was to develop a sensitive quantitative method for detection of anti-AQP4 antibodies that allows clear d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Neurology
دوره 77 9 شماره
صفحات -
تاریخ انتشار 2011